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Quantitative measurement of NNMT reaction product 1-MNA in cultured cells Cellular 1-MNA concentrations were determined using an ultra-sensitive high-resolution AB Sciex 6500 Q-trap mass spectrometer coupled to an Agilent 1260 ultra-high pressure liquid chromatography (LC/MS/MS) system

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Notably, studies have systematically evaluated the compound’s efficacy following oral, intraperitoneal, and intragastric administration, often within the same pathological model [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]